I've found an excellent way to stop the "gay" or "fag" comments is to do something like this.

Pug player: This instance is kinda gay.
Ali: I don't know, it seems pretty straight to me. If it were gay, there might be flags, and maybe also a parade.

For some reason, this usually shuts them down and they don't do it for the remainder of the instance, but it doesn't make them shout me down, either.